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Immunohistochemical study of N-epsilon-carboxymethyl lysine (CML) in human brain: relation to vascular dementia

BACKGROUND: Advanced glycation end-products (AGEs) and their receptor (RAGE) occur in dementia of the Alzheimer's type and diabetic microvascular disease. Accumulation of AGEs relates to risk factors for vascular dementia with ageing, including hypertension and diabetes. Cognitive dysfunction i...

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Detalles Bibliográficos
Autores principales: Southern, Louise, Williams, Jonathan, Esiri, Margaret M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100062/
https://www.ncbi.nlm.nih.gov/pubmed/17939855
http://dx.doi.org/10.1186/1471-2377-7-35