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Role of PP2Cα in cell growth, in radio- and chemosensitivity, and in tumorigenicity

BACKGROUND: PP2Cα is the representative member of the type 2C family of protein phosphatases, and it has recently been implicated in the regulation of p53-, TGFβ-, cyclin-dependent kinase- and apoptosis-signaling. To investigate the role of PP2Cα in cell growth and in radio- and chemosensitivity, wi...

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Detalles Bibliográficos
Autores principales: Lammers, Twan, Peschke, Peter, Ehemann, Volker, Debus, Jürgen, Slobodin, Boris, Lavi, Sara, Huber, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100065/
https://www.ncbi.nlm.nih.gov/pubmed/17941990
http://dx.doi.org/10.1186/1476-4598-6-65