Widespread Epigenetic Abnormalities Suggest a Broad DNA Methylation Erasure Defect in Abnormal Human Sperm

BACKGROUND: Male-factor infertility is a common condition, and etiology is unknown for a high proportion of cases. Abnormal epigenetic programming of the germline is proposed as a possible mechanism compromising spermatogenesis of some men currently diagnosed with idiopathic infertility. During germ...

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Detalles Bibliográficos
Autores principales: Houshdaran, Sahar, Cortessis, Victoria K., Siegmund, Kimberly, Yang, Allen, Laird, Peter W., Sokol, Rebecca Z.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100168/
https://www.ncbi.nlm.nih.gov/pubmed/18074014
http://dx.doi.org/10.1371/journal.pone.0001289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2100168/
https://www.ncbi.nlm.nih.gov/pubmed/18074014
http://dx.doi.org/10.1371/journal.pone.0001289

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