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Role of proteasomes in disease
A functional ubiquitin proteasome system is essential for all eukaryotic cells and therefore any alteration to its components has potential pathological consequences. Though the exact underlying mechanism is unclear, an age-related decrease in proteasome activity weakens cellular capacity to remove...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106367/ https://www.ncbi.nlm.nih.gov/pubmed/18047740 http://dx.doi.org/10.1186/1471-2091-8-S1-S3 |