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Role of proteasomes in disease

A functional ubiquitin proteasome system is essential for all eukaryotic cells and therefore any alteration to its components has potential pathological consequences. Though the exact underlying mechanism is unclear, an age-related decrease in proteasome activity weakens cellular capacity to remove...

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Detalles Bibliográficos
Autor principal: Dahlmann, Burkhardt
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106367/
https://www.ncbi.nlm.nih.gov/pubmed/18047740
http://dx.doi.org/10.1186/1471-2091-8-S1-S3