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Ubiquitin-mediated signalling and Paget's disease of bone

Multiple steps in the RANK-NF-κB signalling pathway are regulated by ubiquitylation. Mutations affecting different components of this pathway, including the ubiquitin binding p62 signalling adapter protein, are found in patients with Paget's disease of bone or related syndromes. Here, we review...

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Detalles Bibliográficos
Autores principales: Layfield, Robert, Shaw, Barry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106369/
https://www.ncbi.nlm.nih.gov/pubmed/18047742
http://dx.doi.org/10.1186/1471-2091-8-S1-S5