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Roles and potential therapeutic targets of the ubiquitin proteasome system in muscle wasting

Muscle wasting, characterized by the loss of protein mass in myofibers, is in most cases largely due to the activation of intracellular protein degradation by the ubiquitin proteasome system (UPS). During the last decade, mechanisms contributing to this activation have been unraveled and key mediato...

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Detalles Bibliográficos
Autores principales: Nury, David, Doucet, Christine, Coux, Olivier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106371/
https://www.ncbi.nlm.nih.gov/pubmed/18047744
http://dx.doi.org/10.1186/1471-2091-8-S1-S7