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Roles and potential therapeutic targets of the ubiquitin proteasome system in muscle wasting
Muscle wasting, characterized by the loss of protein mass in myofibers, is in most cases largely due to the activation of intracellular protein degradation by the ubiquitin proteasome system (UPS). During the last decade, mechanisms contributing to this activation have been unraveled and key mediato...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106371/ https://www.ncbi.nlm.nih.gov/pubmed/18047744 http://dx.doi.org/10.1186/1471-2091-8-S1-S7 |