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ON THE MECHANISM OF DRUG HYDROXYLATION IN RAT LIVER MICROSOMES
The TPNH- and O(2)-dependent drug hydroxylation system of liver microsomes has been studied using normal rats and rats in which the drug-hydroxylating activity has been enhanced by repeated injections of phenobarbital. The oxidative demethylation of aminopyrine is employed as an assay. Optimal condi...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
1965
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106795/ https://www.ncbi.nlm.nih.gov/pubmed/19866674 |