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Germline mutagenesis mediated by Sleeping Beauty transposon system in mice
Following the descovery of its transposition activity in mammalian culture systems, the Sleeping Beauty (SB) transposon has since been applied to achieve germline mutagenesis in mice. Initially, the transposition efficiency was found to be low in cultured systems, but its activity in germ cells was...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106844/ https://www.ncbi.nlm.nih.gov/pubmed/18047691 http://dx.doi.org/10.1186/gb-2007-8-s1-s14 |