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Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy

Viral and transposon vectors have been employed in gene therapy as well as functional genomics studies. However, the goals of gene therapy and functional genomics are entirely different; gene therapists hope to avoid altering endogenous gene expression (especially the activation of oncogenes), where...

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Detalles Bibliográficos
Autores principales: Hackett, Christopher S, Geurts, Aron M, Hackett, Perry B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106846/
https://www.ncbi.nlm.nih.gov/pubmed/18047689
http://dx.doi.org/10.1186/gb-2007-8-s1-s12