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Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives

To meet the increasing demand of linking sequence information to gene function in vertebrate models, genetic modifications must be introduced and their effects analyzed in an easy, controlled, and scalable manner. In the mouse, only about 10% (estimate) of all genes have been knocked out, despite co...

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Detalles Bibliográficos
Autores principales: Mátés, Lajos, Izsvák, Zsuzsanna, Ivics, Zoltán
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106849/
https://www.ncbi.nlm.nih.gov/pubmed/18047686
http://dx.doi.org/10.1186/gb-2007-8-s1-s1