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Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives
To meet the increasing demand of linking sequence information to gene function in vertebrate models, genetic modifications must be introduced and their effects analyzed in an easy, controlled, and scalable manner. In the mouse, only about 10% (estimate) of all genes have been knocked out, despite co...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106849/ https://www.ncbi.nlm.nih.gov/pubmed/18047686 http://dx.doi.org/10.1186/gb-2007-8-s1-s1 |