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Diphtheria toxin entry into cells is facilitated by low pH
At neutral pH, NH4Cl and chloroquine protected cells against diphtheria toxin. A brief exposure of the cells to low pH (4.5-5.5) at 37 degrees completely abolished this protection. When, to cells preincubated with diphtheria toxin and NH4Cl, neutralizing amounts of anti-diphtheria toxin were added b...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1980
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110776/ https://www.ncbi.nlm.nih.gov/pubmed/7462324 |