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Modulation of Bacterial Type III Secretion System by a Spermidine Transporter Dependent Signaling Pathway

BACKGROUND: Many gram-negative bacterial pathogens employ Type III secretion systems (T3SS) to inject effector proteins into host cells in infectious processes. METHODOLOGY/PRINCIPAL FINDINGS: By screening a transposon mutant library of P. aeruginosa, we found that mutation of spuDEFGH, which encode...

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Detalles Bibliográficos
Autores principales: Zhou, Lian, Wang, Jing, Zhang, Lian-Hui
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110884/
https://www.ncbi.nlm.nih.gov/pubmed/18074016
http://dx.doi.org/10.1371/journal.pone.0001291