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Clustered Gene Expression Changes Flank Targeted Gene Loci in Knockout Mice

BACKGROUND: Gene expression profiling using microarrays is a powerful technology widely used to study regulatory networks. Profiling of mRNA levels in mutant organisms has the potential to identify genes regulated by the mutated protein. METHODOLOGY/PRINCIPLE FINDINGS: Using tissues from multiple li...

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Detalles Bibliográficos
Autores principales: Valor, Luis M., Grant, Seth G. N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2110885/
https://www.ncbi.nlm.nih.gov/pubmed/18074027
http://dx.doi.org/10.1371/journal.pone.0001303