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DNA replication, chromatin structure, and histone phosphorylation altered by theophylline in synchronized HeLa S3 cells
The onset of DNA replication normally is coincident with an increase in histone 1 phosphorylation and a relaxation in chromatin structure. In this paper we show that 5 mM theophylline, added 2 h after selective detachment to synchronized HeLa-S-3 cells, delays the onset and reduces the rate of DNA s...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1981
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2111767/ https://www.ncbi.nlm.nih.gov/pubmed/7228902 |