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Amplified dihydrofolate reductase genes are located in chromosome regions containing DNA that replicates during the first half of S-phase
To obtain a better understanding of the relationship between metaphase chromosome banding patterns and genome organization, attention was focused on regions of metaphase chromosomes that were found to contain the genes for a specific cellular enzyme, dihydrofolate reductase (DHFR). These studies inv...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1982
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112057/ https://www.ncbi.nlm.nih.gov/pubmed/7061595 |