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Tumor promoter phorbol 12-myristate 13-acetate inhibits mitogen- stimulated Na+/H+ exchange in human epidermoid carcinoma A431 cells
Addition of polypeptide growth factors to cultured cells results in a rapid stimulation of Na+/H+ exchange, which leads to cytoplasmic alkalinization. We studied the effects of the potent tumor promoter phorbol 12-myristate 13-acetate (PMA) on the Na+/H+ exchange system of A431 cells. Stimulation of...
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Lenguaje: | English |
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The Rockefeller University Press
1984
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113392/ https://www.ncbi.nlm.nih.gov/pubmed/6088556 |