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Definition of an N-terminal actin-binding domain and a C-terminal Ca2+ regulatory domain in human brevin
Brevin is a Ca2+-modulated actin-associated protein that will sever F- actin and cap barbed filament ends. Limited proteolysis with chymotrypsin or subtilisin cleaves the molecule approximately in half. Cleavage is approximately 10-fold more rapid in Ca2+ than in EGTA. The two fragments are readily...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1986
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2114174/ https://www.ncbi.nlm.nih.gov/pubmed/3082893 |