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Diverse effects of beta-tubulin mutations on microtubule formation and function
We have used in vitro mutagenesis and gene replacement to construct five new cold-sensitive mutations in TUB2, the sole gene encoding beta- tubulin in the yeast Saccharomyces cerevisiae. These and one previously isolated tub2 mutant display diverse phenotypes that have allowed us to define the funct...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1988
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2115142/ https://www.ncbi.nlm.nih.gov/pubmed/3290223 |