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Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene crm1+ which encodes a 115- kD protein preferentially localized in the nucleus and its periphery
We isolated a novel class of Schizosaccharomyces pombe cold-sensitive mutants with deformed nuclear chromosome domains consisting of thread- or rodlike condensed segments at restrictive temperature. Their mutations were mapped in a novel, identical locus designated crm1 (chromosomal region maintenan...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1989
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2115495/ https://www.ncbi.nlm.nih.gov/pubmed/2647765 |