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Neomycin is a potent secretagogue of mast cells that directly activates a GTP-binding protein involved in exocytosis
When loaded alongside GTP-gamma-S into ATP-permeabilized cells, neomycin, at concentrations below 1 mM, inhibits GTP-gamma-S-induced histamine secretion and phosphatidic acid formation (Cockcroft, S., and B. D. Gomperts, 1985. Nature (Lond.). 314: 534-536; Aridor, M., L. M. Traub, and R. Sagi-Eisenb...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2116356/ https://www.ncbi.nlm.nih.gov/pubmed/1702786 |