Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1α

BACKGROUND: Searching for novel molecular markers that dependably predict or indicate responses of human cancer cells to epidermal growth factor receptor (EGFR)-targeted therapy is strongly warranted. The purpose of the current study was to evaluate hypoxia-inducible factor-1α (HIF-1α) as a novel re...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Yang, Liang, Ke, Li, Xinqun, Fan, Zhen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117021/
https://www.ncbi.nlm.nih.gov/pubmed/17931419
http://dx.doi.org/10.1186/1476-4598-6-63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117021/
https://www.ncbi.nlm.nih.gov/pubmed/17931419
http://dx.doi.org/10.1186/1476-4598-6-63

Ejemplares similares