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Full-Exon Resequencing Reveals Toll-Like Receptor Variants Contribute to Human Susceptibility to Tuberculosis Disease

Tuberculosis (TB) is the leading cause of death worldwide due to an infectious agent. Data have accumulated over decades suggesting that variability in human susceptibility to TB disease has a genetic component. Toll-like receptors (TLRs) play a critical role in initiating the innate immune response...

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Detalles Bibliográficos
Autores principales: Ma, Xin, Liu, Yuhua, Gowen, Brian B., Graviss, Edward A., Clark, Andrew G., Musser, James M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117342/
https://www.ncbi.nlm.nih.gov/pubmed/18091991
http://dx.doi.org/10.1371/journal.pone.0001318