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Identification of Novel High-Frequency DNA Methylation Changes in Breast Cancer

Recent data have revealed that epigenetic alterations, including DNA methylation and chromatin structure changes, are among the earliest molecular abnormalities to occur during tumorigenesis. The inherent thermodynamic stability of cytosine methylation and the apparent high specificity of the altera...

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Detalles Bibliográficos
Autores principales: Ordway, Jared M., Budiman, Muhammad A., Korshunova, Yulia, Maloney, Rebecca K., Bedell, Joseph A., Citek, Robert W., Bacher, Blaire, Peterson, Seth, Rohlfing, Tracy, Hall, Jacqueline, Brown, Robert, Lakey, Nathan, Doerge, Rebecca W., Martienssen, Robert A., Leon, Jorge, McPherson, John D., Jeddeloh, Jeffrey A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117343/
https://www.ncbi.nlm.nih.gov/pubmed/18091988
http://dx.doi.org/10.1371/journal.pone.0001314