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A New In Vitro Strand Transfer Assay for Monitoring Bacterial Class 1 Integron Recombinase IntI1 Activity

IntI1 integrase is a tyrosine recombinase involved in the mobility of antibiotic resistance gene cassettes within bacterial class 1 integrons. Recent data have shown that its recombination specifically involves the bottom strand of the attC site, but the exact mechanism of the reaction is still uncl...

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Detalles Bibliográficos
Autores principales: Dubois, Véronique, Debreyer, Carole, Litvak, Simon, Quentin, Claudine, Parissi, Vincent
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117344/
https://www.ncbi.nlm.nih.gov/pubmed/18091989
http://dx.doi.org/10.1371/journal.pone.0001315