Uptake of Leishmania major by dendritic cells is mediated by Fcγ receptors and facilitates acquisition of protective immunity

Uptake of Leishmania major by dendritic cells (DCs) results in activation and interleukin (IL)-12 release. Infected DCs efficiently stimulate CD4(−) and CD8(−) T cells and vaccinate against leishmaniasis. In contrast, complement receptor 3–dependent phagocytosis of L. major by macrophages (MΦ) leads...

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Detalles Bibliográficos
Autores principales: Woelbing, Florian, Kostka, Susanna Lopez, Moelle, Katharina, Belkaid, Yasmine, Sunderkoetter, Cord, Verbeek, Sjef, Waisman, Ari, Nigg, Axel P., Knop, Juergen, Udey, Mark C., von Stebut, Esther
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118064/
https://www.ncbi.nlm.nih.gov/pubmed/16418399
http://dx.doi.org/10.1084/jem.20052288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118064/
https://www.ncbi.nlm.nih.gov/pubmed/16418399
http://dx.doi.org/10.1084/jem.20052288

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