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Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning

In the absence of irradiation or other cytoreductive conditioning, endogenous hematopoietic stem cells (HSCs) are thought to fill the unique niches within the bone marrow that allow maintenance of full hematopoietic potential and thus prevent productive engraftment of transplanted donor HSCs. By tra...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Deepta, Rossi, Derrick J., Bryder, David, Weissman, Irving L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118067/
https://www.ncbi.nlm.nih.gov/pubmed/16380511
http://dx.doi.org/10.1084/jem.20051714