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Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning
In the absence of irradiation or other cytoreductive conditioning, endogenous hematopoietic stem cells (HSCs) are thought to fill the unique niches within the bone marrow that allow maintenance of full hematopoietic potential and thus prevent productive engraftment of transplanted donor HSCs. By tra...
Autores principales: | Bhattacharya, Deepta, Rossi, Derrick J., Bryder, David, Weissman, Irving L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118067/ https://www.ncbi.nlm.nih.gov/pubmed/16380511 http://dx.doi.org/10.1084/jem.20051714 |
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