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LAT-mediated signaling in CD4(+)CD25(+) regulatory T cell development

Engagement of the T cell receptor for antigen (TCR) induces formation of signaling complexes mediated through the transmembrane adaptor protein, the linker for activation of T cells (LAT). LAT plays an important role in T cell development, activation, and homeostasis. A knock-in mutation at Tyr136,...

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Detalles Bibliográficos
Autores principales: Koonpaew, Surapong, Shen, Shudan, Flowers, Lawrence, Zhang, Weiguo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118069/
https://www.ncbi.nlm.nih.gov/pubmed/16380508
http://dx.doi.org/10.1084/jem.20050903