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LAT-mediated signaling in CD4(+)CD25(+) regulatory T cell development
Engagement of the T cell receptor for antigen (TCR) induces formation of signaling complexes mediated through the transmembrane adaptor protein, the linker for activation of T cells (LAT). LAT plays an important role in T cell development, activation, and homeostasis. A knock-in mutation at Tyr136,...
Autores principales: | Koonpaew, Surapong, Shen, Shudan, Flowers, Lawrence, Zhang, Weiguo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118069/ https://www.ncbi.nlm.nih.gov/pubmed/16380508 http://dx.doi.org/10.1084/jem.20050903 |
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