Cargando…

MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock

Septic shock is a leading cause of morbidity and mortality. However, genetic factors predisposing to septic shock are not fully understood. Excessive production of proinflammatory cytokines, particularly tumor necrosis factor (TNF)-α, and the resultant severe hypotension play a central role in the p...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Qun, Wang, Xianxi, Nelin, Leif D., Yao, Yongxue, Matta, Ranyia, Manson, Mary E., Baliga, Reshma S., Meng, Xiaomei, Smith, Charles V., Bauer, John A., Chang, Cheong-Hee, Liu, Yusen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118076/
https://www.ncbi.nlm.nih.gov/pubmed/16380513
http://dx.doi.org/10.1084/jem.20051794