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Chewing the fat on natural killer T cell development

Natural killer T cells (NKT cells) are selected in the thymus by self-glycolipid antigens presented by CD1d molecules. It is currently thought that one specific component of the lysosomal processing pathway, which leads to the production of isoglobotrihexosylceramide (iGb3), is essential for normal...

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Detalles Bibliográficos
Autores principales: Godfrey, Dale I., McConville, Malcolm J., Pellicci, Daniel G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118098/
https://www.ncbi.nlm.nih.gov/pubmed/17000869
http://dx.doi.org/10.1084/jem.20061787