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Chewing the fat on natural killer T cell development
Natural killer T cells (NKT cells) are selected in the thymus by self-glycolipid antigens presented by CD1d molecules. It is currently thought that one specific component of the lysosomal processing pathway, which leads to the production of isoglobotrihexosylceramide (iGb3), is essential for normal...
Autores principales: | Godfrey, Dale I., McConville, Malcolm J., Pellicci, Daniel G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118098/ https://www.ncbi.nlm.nih.gov/pubmed/17000869 http://dx.doi.org/10.1084/jem.20061787 |
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