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Synergy between the pre–T cell receptor and Notch: cementing the αβ lineage choice
Notch1 signaling suppresses B cell development and promotes T lineage commitment in thymus-seeding hematopoietic progenitors. Notch1 is also activated in early T cell progenitors, but the functions of these later Notch signals have not been clearly defined. Recent studies reveal that Notch signaling...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118108/ https://www.ncbi.nlm.nih.gov/pubmed/17000868 http://dx.doi.org/10.1084/jem.20060998 |