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Resolution of a chronic viral infection after interleukin-10 receptor blockade

A defining characteristic of persistent viral infections is the loss and functional inactivation of antiviral effector T cells, which prevents viral clearance. Interleukin-10 (IL-10) suppresses cellular immune responses by modulating the function of T cells and antigen-presenting cells. In this pape...

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Detalles Bibliográficos
Autores principales: Ejrnaes, Mette, Filippi, Christophe M., Martinic, Marianne M., Ling, Eleanor M., Togher, Lisa M., Crotty, Shane, von Herrath, Matthias G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118120/
https://www.ncbi.nlm.nih.gov/pubmed/17030951
http://dx.doi.org/10.1084/jem.20061462