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Resolution of a chronic viral infection after interleukin-10 receptor blockade
A defining characteristic of persistent viral infections is the loss and functional inactivation of antiviral effector T cells, which prevents viral clearance. Interleukin-10 (IL-10) suppresses cellular immune responses by modulating the function of T cells and antigen-presenting cells. In this pape...
Autores principales: | Ejrnaes, Mette, Filippi, Christophe M., Martinic, Marianne M., Ling, Eleanor M., Togher, Lisa M., Crotty, Shane, von Herrath, Matthias G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118120/ https://www.ncbi.nlm.nih.gov/pubmed/17030951 http://dx.doi.org/10.1084/jem.20061462 |
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