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High affinity germinal center B cells are actively selected into the plasma cell compartment

A hallmark of T cell–dependent immune responses is the progressive increase in the ability of serum antibodies to bind antigen and provide immune protection. Affinity maturation of the antibody response is thought to be connected with the preferential survival of germinal centre (GC) B cells that ha...

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Detalles Bibliográficos
Autores principales: Phan, Tri Giang, Paus, Didrik, Chan, Tyani D., Turner, Marian L., Nutt, Stephen L., Basten, Antony, Brink, Robert
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118125/
https://www.ncbi.nlm.nih.gov/pubmed/17030950
http://dx.doi.org/10.1084/jem.20061254