T cell receptor for antigen induces linker for activation of T cell–dependent activation of a negative signaling complex involving Dok-2, SHIP-1, and Grb-2

Adaptor proteins positively or negatively regulate the T cell receptor for antigen (TCR) signaling cascade. We report that after TCR stimulation, the inhibitory adaptor downstream of kinase (Dok)-2 and its homologue Dok-1 are involved in a multimolecular complex including the lipid phosphatase Src h...

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Detalles Bibliográficos
Autores principales: Dong, Shen, Corre, Béatrice, Foulon, Eliane, Dufour, Evelyne, Veillette, André, Acuto, Oreste, Michel, Frédérique
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118126/
https://www.ncbi.nlm.nih.gov/pubmed/17043143
http://dx.doi.org/10.1084/jem.20060650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118126/
https://www.ncbi.nlm.nih.gov/pubmed/17043143
http://dx.doi.org/10.1084/jem.20060650

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