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A role for IRF3-dependent RXRα repression in hepatotoxicity associated with viral infections

Viral infections and antiviral responses have been linked to several metabolic diseases, including Reye's syndrome, which is aspirin-induced hepatotoxicity in the context of a viral infection. We identify an interferon regulatory factor 3 (IRF3)–dependent but type I interferon–independent pathw...

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Detalles Bibliográficos
Autores principales: Chow, Edward K., Castrillo, Antonio, Shahangian, Arash, Pei, Liming, O'Connell, Ryan M., Modlin, Robert L., Tontonoz, Peter, Cheng, Genhong
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118146/
https://www.ncbi.nlm.nih.gov/pubmed/17074929
http://dx.doi.org/10.1084/jem.20060929