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A role for IRF3-dependent RXRα repression in hepatotoxicity associated with viral infections
Viral infections and antiviral responses have been linked to several metabolic diseases, including Reye's syndrome, which is aspirin-induced hepatotoxicity in the context of a viral infection. We identify an interferon regulatory factor 3 (IRF3)–dependent but type I interferon–independent pathw...
Autores principales: | Chow, Edward K., Castrillo, Antonio, Shahangian, Arash, Pei, Liming, O'Connell, Ryan M., Modlin, Robert L., Tontonoz, Peter, Cheng, Genhong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118146/ https://www.ncbi.nlm.nih.gov/pubmed/17074929 http://dx.doi.org/10.1084/jem.20060929 |
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