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Insulin-induced remission in new-onset NOD mice is maintained by the PD-1–PD-L1 pathway

The past decade has seen a significant increase in the number of potentially tolerogenic therapies for treatment of new-onset diabetes. However, most treatments are antigen nonspecific, and the mechanism for the maintenance of long-term tolerance remains unclear. In this study, we developed an antig...

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Detalles Bibliográficos
Autores principales: Fife, Brian T., Guleria, Indira, Gubbels Bupp, Melanie, Eagar, Todd N., Tang, Qizhi, Bour-Jordan, Helene, Yagita, Hideo, Azuma, Miyuki, Sayegh, Mohamed H., Bluestone, Jeffrey A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118162/
https://www.ncbi.nlm.nih.gov/pubmed/17116737
http://dx.doi.org/10.1084/jem.20061577