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Bcl-xl does not have to bind Bax to protect T cells from death

Activated T cells die when antigen disappears from animals. This death is caused by proteins related to Bcl-2. Two hypotheses have been suggested to explain the actions of the different types of Bcl-2 proteins. One hypothesis suggests that, when T cells prepare to die, Bak and Bax, the proteins that...

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Detalles Bibliográficos
Autores principales: Liu, Xinqi, Zhu, Yanan, Dai, Shaodong, White, Janice, Peyerl, Fred, Kappler, John W., Marrack, Philippa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118172/
https://www.ncbi.nlm.nih.gov/pubmed/17158961
http://dx.doi.org/10.1084/jem.20061151