Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences

It is thought that gene conversion (GCV) and somatic hypermutation (SHM) of immunoglobulin (Ig) genes occur in two steps: the generation of uracils in DNA by activation-induced cytidine deaminase, followed by their subsequent repair by various DNA repair pathways to generate sequence-diversified pro...

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Detalles Bibliográficos
Autores principales: Yang, Shu Yuan, Fugmann, Sebastian D., Schatz, David G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118177/
https://www.ncbi.nlm.nih.gov/pubmed/17178919
http://dx.doi.org/10.1084/jem.20061835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118177/
https://www.ncbi.nlm.nih.gov/pubmed/17178919
http://dx.doi.org/10.1084/jem.20061835

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