Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor γ activity

Colitis involves immune cell–mediated tissue injuries, but the contribution of epithelial cells remains largely unclear. Vanin-1 is an epithelial ectoenzyme with a pantetheinase activity that provides cysteamine/cystamine to tissue. Using the 2,4,6-trinitrobenzene sulfonic acid (TNBS)-colitis model...

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Detalles Bibliográficos
Autores principales: Berruyer, Carole, Pouyet, Laurent, Millet, Virginie, Martin, Florent M., LeGoffic, Aude, Canonici, Alexandra, Garcia, Stéphane, Bagnis, Claude, Naquet, Philippe, Galland, Franck
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118186/
https://www.ncbi.nlm.nih.gov/pubmed/17145956
http://dx.doi.org/10.1084/jem.20061640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118186/
https://www.ncbi.nlm.nih.gov/pubmed/17145956
http://dx.doi.org/10.1084/jem.20061640

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