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B cell–deficient NOD.H-2h4 mice have CD4(+)CD25(+) T regulatory cells that inhibit the development of spontaneous autoimmune thyroiditis
Wild-type (WT) NOD.H-2h4 mice develop spontaneous autoimmune thyroiditis (SAT) when given 0.05% NaI in their drinking water, whereas B cell–deficient NOD.H-2h4 mice are SAT resistant. To test the hypothesis that resistance of B cell–deficient mice to SAT was due to the activity of regulatory CD4(+)C...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118195/ https://www.ncbi.nlm.nih.gov/pubmed/16446379 http://dx.doi.org/10.1084/jem.20051438 |