The Bcl10–Malt1 complex segregates FcɛRI-mediated nuclear factor κB activation and cytokine production from mast cell degranulation

Mast cells are pivotal effector cells in IgE-mediated allergic inflammatory diseases. Central for mast cell activation are signals from the IgE receptor FcɛRI, which induce cell degranulation with the release of preformed mediators and de novo synthesis of proinflammatory leukotrienes and cytokines....

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Detalles Bibliográficos
Autores principales: Klemm, Stefanie, Gutermuth, Jan, Hültner, Lothar, Sparwasser, Tim, Behrendt, Heidrun, Peschel, Christian, Mak, Tak W., Jakob, Thilo, Ruland, Jürgen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118204/
https://www.ncbi.nlm.nih.gov/pubmed/16432253
http://dx.doi.org/10.1084/jem.20051982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118204/
https://www.ncbi.nlm.nih.gov/pubmed/16432253
http://dx.doi.org/10.1084/jem.20051982

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