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Impaired response to Listeria in H2-M3–deficient mice reveals a nonredundant role of MHC class Ib–specific T cells in host defense

The major histocompatibility complex (MHC) class Ib molecule H2-M3 primes the rapid expansion of CD8(+) T cells by presenting N-formylated bacterial peptides. However, the significance of H2-M3–restricted T cells in host defense against bacteria is unclear. We generated H2-M3–deficient mice to inves...

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Detalles Bibliográficos
Autores principales: Xu, Honglin, Chun, Taehoon, Choi, Hak-Jong, Wang, Bin, Wang, Chyung-Ru
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118219/
https://www.ncbi.nlm.nih.gov/pubmed/16476767
http://dx.doi.org/10.1084/jem.20051866