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Impaired response to Listeria in H2-M3–deficient mice reveals a nonredundant role of MHC class Ib–specific T cells in host defense
The major histocompatibility complex (MHC) class Ib molecule H2-M3 primes the rapid expansion of CD8(+) T cells by presenting N-formylated bacterial peptides. However, the significance of H2-M3–restricted T cells in host defense against bacteria is unclear. We generated H2-M3–deficient mice to inves...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118219/ https://www.ncbi.nlm.nih.gov/pubmed/16476767 http://dx.doi.org/10.1084/jem.20051866 |