A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke

It remains unclear why some individuals are susceptible to excitotoxicity after stroke. A possible explanation is impaired glutamate uptake. We have found a highly prevalent polymorphism in the promoter of the glutamate transporter EAAT2 gene that abolishes a putative regulatory site for activator p...

Descripción completa

Detalles Bibliográficos
Autores principales: Mallolas, Judith, Hurtado, Olivia, Castellanos, Mar, Blanco, Miguel, Sobrino, Tomás, Serena, Joaquín, Vivancos, José, Castillo, José, Lizasoain, Ignacio, Moro, María A., Dávalos, Antoni
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118230/
https://www.ncbi.nlm.nih.gov/pubmed/16520390
http://dx.doi.org/10.1084/jem.20051979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118230/
https://www.ncbi.nlm.nih.gov/pubmed/16520390
http://dx.doi.org/10.1084/jem.20051979

Ejemplares similares