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A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke

It remains unclear why some individuals are susceptible to excitotoxicity after stroke. A possible explanation is impaired glutamate uptake. We have found a highly prevalent polymorphism in the promoter of the glutamate transporter EAAT2 gene that abolishes a putative regulatory site for activator p...

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Detalles Bibliográficos
Autores principales:	Mallolas, Judith, Hurtado, Olivia, Castellanos, Mar, Blanco, Miguel, Sobrino, Tomás, Serena, Joaquín, Vivancos, José, Castillo, José, Lizasoain, Ignacio, Moro, María A., Dávalos, Antoni
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118230/ https://www.ncbi.nlm.nih.gov/pubmed/16520390 http://dx.doi.org/10.1084/jem.20051979

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